Contents 1 History 2 Activities 2.1 Biomedical research 2.1.1 Major investments 2.1.2 Major Overseas Programmes 2.1.3 Seeding Drug Discovery Initiative 2.2 Support for Open Access and Open Data 2.3 Membership in the Global Health Innovative Technology Fund (GHIT) 2.4 Public engagement and the Wellcome Collection 2.4.1 Wellcome Book Prize 3 Investments 3.1 Purchase of the Co-operative Farms business 4 Headquarters 5 See also 6 References 7 External links


History[edit] The Trust was established to administer the fortune of the American-born pharmaceutical magnate Sir Henry Wellcome.[8] Its income was derived from what was originally called Burroughs Wellcome, later renamed in the UK as the Wellcome Foundation Ltd.[9] In 1986, the trust sold 25% of Wellcome plc stock to the public. Overseen by incoming Director of Finance Ian Macgregor, this marked the beginning of a period of financial growth that saw the Trust's value increase by almost £14bn in 14 years, as their interests moved beyond the bounds of the pharmaceutical industry.[10] In 1995, the trust divested itself of any interest in pharmaceuticals by selling all remaining stock to Glaxo plc, the company's historic British rival, creating GlaxoWellcome plc. In 2000, the Wellcome name disappeared from the drug business altogether when GlaxoWellcome merged with SmithKline Beecham, to form GlaxoSmithKline plc.[11]


Activities[edit] Biomedical research[edit] Major investments[edit] The Trust funds or co-funds a number of major biomedical research initiatives:[12] Avon Longitudinal Study of Parents and Children (ALSPAC), a cohort study of children born in England during 1991 and 1992. The Cancer Genome Project at the Wellcome Trust Sanger Institute. The Diamond Light Source, the UK's national synchrotron science facility in Oxfordshire. Developing Excellence in Leadership, Training and Science Initiative (DELTAS), a collaboration with the Department for International Development (DFID) to establish cutting-edge research and training programmes across the African continent. The Ebola Emergency Initiative, a fast-tracked research programme with the goal of identifying clinical and public health interventions to counter the West African Ebola Epidemic. The Juvenile Diabetes Research Foundation/ Wellcome Trust Diabetes and Inflammation Laboratory facilitates research into the genetic component of type 1 diabetes and is based in the Cambridge Institute for Medical Research. The Seeding Drug Discovery Initiative. The Structural Genomics Consortium, an international organisation focussing on three-dimensional structures of proteins of medical relevance with an emphasis on open data. The Wellcome Trust Sanger Institute, a non-profit, British genomics and genetics research institute.[13] UK Biobank and the UK Biobank Ethics and Governance Council. Major Overseas Programmes[edit] The KEMRI-Wellcome Trust Research Programme, established in 1989 in partnership with the Kenya Medical Research Institute.[14] The Malawi-Liverpool-Wellcome Trust Clinical Research Programme, established in 1995. The Africa Centre for Health and Population Studies in South Africa, established in 1998 in partnership with the South African Medical Research Council. The Wellcome Trust-Mahidol University-Oxford Tropical Medicine Research Programme in Thailand and Laos, established in 1979. The Vietnam Research Programme and Oxford University Clinical Research Unit in Ho Chi Minh City and Hanoi. Seeding Drug Discovery Initiative[edit] Also known as SDDI, this five year initiative started in October 2005 with the remit "to facilitate the development of drug-like small molecules that address unmet medical needs." SDDI was based in London and managed by Richard Davis.[15] Through early 2010, SDDI had provided more than £80 million across 30 projects split between academic institutions and companies.[15] To early 2010, all but one of the company recipients were either start-ups or spin-outs.[15] In May 2010, an additional £110 million was added to the SDDI fund with the intent to extend the initiative for an additional 5 years.[16] Support for Open Access and Open Data[edit] The Wellcome Trust plays an important role in encouraging publication of research in open access repositories[17] such as Europe PubMed Central (EuropePMC). The Wellcome Trust believes that maximising the distribution of these papers - by providing free, online access - is the most effective way of ensuring that the research can be accessed, read and built upon. In turn, this will foster a richer research culture.[citation needed] In 2016, the Wellcome Trust partnered with the US National Institutes of Health (NIH) and the Howard Hughes Medical Institute to launch the Open Science Prize[18] to "help develop services, tools and platforms that enable open content to be discovered, assessed and re-used in ways that will advance discovery and spark innovation."[18] In 2016, Wellcome Trust announced that it would be launching Wellcome Open Research,[19] an open access publication system running on the F1000 Research platform.[20] Article Processing Charges will be covered directly by Wellcome Trust. Paper from the system are now indexed in PubMed Central.[21] Membership in the Global Health Innovative Technology Fund (GHIT)[edit] In the summer of 2015, the Wellcome Trust joined the Japanese government, 7 Japanese pharmaceutical and diagnostics companies, The Bill and Melinda Gates Foundation, and the United Nations Development Program as funding partner of the Global Health Innovative Technology Fund (GHIT), which funds scientific research and development for anti-infectives and diagnostics for diseases that primarily affect the developing world.[22][23] Public engagement and the Wellcome Collection[edit] Main article: Wellcome Collection In June 2007, the Wellcome Building reopened after refurbishment as a public venue, housing the Wellcome Collection, the Wellcome Trust Centre for the History of Medicine at University College London and the Wellcome Library.[24] The aim of the Wellcome Collection is to enhance public understanding of medical science and history. The building contains gallery spaces, conference facilities, space for debates, drama and workshops, a café and a bookshop. The galleries show a small sample of works from Sir Henry Wellcome's collection, and host a programme of events and exhibitions. The Wellcome Collection and exhibitions are open to the public free of charge six days a week.[25] The Wellcome Collection and Wellcome Library are members of The London Museums of Health & Medicine. Wellcome Book Prize[edit] Main article: Wellcome Book Prize The Wellcome Trust sponsors an annual book prize, the Wellcome Book Prize, which "aims to excite public interest and encourage debate" around medicine and health.[26]


Investments[edit] This section needs expansion. You can help by adding to it. (March 2016) Purchase of the Co-operative Farms business[edit] In August 2014, the Wellcome Trust bought the Co-operative Group's farm business (renamed Farmcare) for £249 million. This comprised "15,997 hectares (39,533 acres) of freehold and third party owned land, 15 farms, including three pack houses, over 100 residential properties, and 27 commercial properties."[27]


Headquarters[edit] The Wellcome Trust's Gibbs Building on Euston Road The Wellcome Trust's operations are run from two buildings on Euston Road in London. The Wellcome Building, at 183 Euston Road, built in 1932 in Portland stone houses the Wellcome Collection and the adjoining glass and steel building at 215 Euston Road is the Gibbs Building, by Hopkins Architects, which opened in 2004 as the administrative headquarters of the Wellcome Trust.


See also[edit] Heads of International Research Organizations List of wealthiest charitable foundations


References[edit] ^ "Eliza Manningham-Buller to be next Chair of the Wellcome Trust".  ^ Van Noorden, Richard (2013). "Clinician to head Wellcome Trust: Jeremy Farrar to lead one of world’s largest research charities". Nature. 497 (7447): 19. doi:10.1038/497019a.  ^ "Wellcome Trust aims to increase spend to £5 billion over next 5 years".  ^ a b "Wellcome's charitable spend reaches record levels". Wellcome Trust. 2017.  ^ "Charity Commission factsheet for the Wellcome Trust". Charity Commission for England and Wales. 17 December 2015.  ^ Alok Jha (9 April 2012), "Wellcome Trust joins 'academic spring' to open up science", The Guardian  ^ Andrew Jack (2012-04-10). "Wellcome challenges science journals". Financial Times. Retrieved 2012-04-16.  (registration required) ^ "History of Henry Wellcome".  ^ Hall, A. R. & Bembridge, B. A. Physic and philanthropy: a history of the Wellcome Trust 1936–1986. Cambridge (UK): Cambridge University Press, 1986. ISBN 0-521-32639-7 ^ briandeer.com Sunday Times investigation, February 1994] ^ "Henry Wellcome's legacy". Wellcome.ac.uk. Retrieved 2016-05-21.  ^ "Biomedical science funded projects".  ^ "MRC Centre United Kingdom: Wellcome Trust Sanger Institute". Medical Research Council. Retrieved 2008-12-22.  ^ "Kenya and the KEMRI-Wellcome Trust Research Programme".  ^ a b c "A Wellcome experiment in seeding drug discovery". Nature Reviews Drug Discovery (PDF)|format= requires |url= (help). 9 (3): 178–180. March 2010. doi:10.1038/nrd3130. (subscription required) ^ "Wellcome Trust extends Seeding Drug Discovery initiative". TMRM. AngelNews. 14 May 2010. Retrieved 4 July 2013.  ^ "Wellcome Trust position statement in support of open and unrestricted access to published research".  ^ a b "The Open Science Prize".  ^ "Wellcome Open Research provides all Wellcome researchers with a place to rapidly publish any results they think are worth sharing". wellcomeopenresearch.org. Retrieved 2016-11-08.  ^ "Wellcome Open Research is now accepting submissions". Discussions – F1000 Research. 2016-10-17. Retrieved 2016-11-08.  ^ "Archive of "Wellcome Open Research"". www.ncbi.nlm.nih.gov. Retrieved 2017-06-14.  ^ “Japan in pioneering partnership to fund global health research”, by Andrew Jack, Financial Times, May 30, 2013 ^ “Japanese Global Health Fund Welcomes the Wellcome Trust and Sysmex Corporation as New Funders and ANA, Morrison & Foerster, and Yahoo! Japan as New Sponsors”, PR Newswire, June 3, 2015, <http://www.prnewswire.com/news-releases/japanese-global-health-fund-welcomes-the-wellcome-trust-and-sysmex-corporation-as-new-funders-and-ana-morrison--foerster-and-yahoo-japan-as-new-sponsors-300093066.html>, accessed on 9/28/2015 ^ "The Wellcome Library".  ^ "Wellcome Collection opening hours".  ^ "About the Wellcome Book Prize | Wellcome Book Prize". wellcomebookprize.org. Retrieved 2017-03-15.  ^ "Wellcome Trust acquires the Co-operative Group's farms business". Wellcome.ac.uk. 2014-08-04. Retrieved 2016-05-21. 


External links[edit] Wikimedia Commons has media related to Files from Wellcome Images. Wellcome Trust main website Other Wellcome Trust websites Scientific Conferences supported by the Wellcome Trust Ex Memoria - Wellcome Trust Awarded Film Surgery Live, a Wellcome Collection collaboration with Channel 4 European Society for Clinical Microbioloy and Infectious Diseases Federation of European Biochemical Societies European Federation of Pharmaceutical Societies International Society for Infectious Diseases v t e Wellcome Trust Centres and institutes Current Francis Crick Institute Gurdon Institute Sainsbury Wellcome Centre for Neural Circuits and Behaviour Science Learning Centres WTC for Cell-Matrix Research WTC for Gene Regulation and Expression WTC for Human Genetics WTC for Mitochondrial Research WTC for Molecular Parasitology WTC for Neuroimaging WTC for Stem Cell Research Wellcome Trust Sanger Institute Former Wellcome Trust Centre for the History of Medicine Wellcome Research Laboratories Projects and facilities 1000 Genomes Project Big Picture Cambridge Biomedical Campus Cancer Genome Project ChEMBL COSMIC cancer database DECIPHER Diamond Light Source eLife Ensembl Farmcare Genome Reference Consortium Human Genome Project Malawi Liverpool Wellcome Trust MEROPS Pfam Rfam UK Biobank Wellcome Collection Wellcome Genome Campus Wellcome Library WormBase Board of Governors Tobias Bonhoeffer Alan Brown Damon Buffini William Burns Kay Davies Michael Ferguson Bryan Grenfell Richard Hynes Anne Johnson Eliza Manningham-Buller Peter Rigby Executive Board Jeremy Farrar Stephen Caddick Simon Chaplin Tim Livett Clare Matterson Ted Smith Danny Truell Former directors Peter Williams (1965–1991) Bridget Ogilvie (1991–1998) Michael Dexter (1998–2008) Mark Walport (2003–2013) Other key people William Castell Dominic Cadbury Harold Cook Oliver Franks Roger Gibbs Henry Dale Roy Porter David Steel David Stuart John Sulston Henry Wellcome Awards and fellowships Capital Awards Collaborative Awards in Science Investigator Awards in Science Institutional Strategic Support Fund Science Strategic Award Sir Henry Dale Fellowship Sir Henry Wellcome Postdoctoral Fellowship Wellcome Book Prize Wellcome Image Awards Wellcome Trust Centre Wellcome Trust Principal Research Fellow Wellcome Trust Senior Research Fellow Category v t e Francis Crick Institute Funded by Cancer Research UK Imperial College London King's College London Medical Research Council University College London Wellcome Trust Senior staff Simon Boulton Doreen Cantrell David Cooksey Julian Downward Jeremy Farrar Steve Gamblin Peter Gruss Adrian Hayday Tim Hunt Malcolm Irving Harpal Kumar Robin Lovell-Badge Tomas Lindahl Paul Nurse Anne O'Garra Keith Peters Geraint Rees John Skehel Jim Smith Richard Treisman Frank Uhlmann Jean-Paul Vincent David Willetts Philip Yea Incorporating National Institute for Medical Research London Research Institute v t e Science and technology in the United Kingdom Economy of the United Kingdom official bodies and personnel Chief Scientific Adviser to the Ministry of 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