Contents 1 Structure 1.1 Development 1.1.1 Male 1.1.2 Female 2 Function 2.1 Sexual differentiation 3 History 4 Additional images 5 See also 6 References 7 External links


Structure[edit] The mesonephric duct connects the primitive kidney, the mesonephros, to the cloaca and serves as the anlage for certain male reproductive organs. Development[edit] Wolffian duct (red) degenerates in females (middle image) and develops in males (bottom). Diagrams to illustrate the changes in the cloaca in mammals during development. A, early embryonic stage, showing the cloaca receiving the urinary bladder, the rectum, and the Wolffian duct, as in the lower vertebrates. B, later stage, showing the beginning of the fold which divides the cloaca into a ventral urogenital sinus which receives the urinary bladder, Wolffian ducts, and ureters, and into a dorsal part which receives the rectum. C, further progress of the fold, dividing the cloaca into urogenital sinus and rectum; the ureter has separated from the Wolffian duct and is shifting anteriorly. D, completion of the fold, showing complete separation of the cloaca into ventral urogenital sinus and dorsal rectum. In both the male and the female the mesonephric duct develops into the trigone of urinary bladder, a part of the bladder wall. However, further development differentiates between the sexes in the development of the urinary and reproductive organs. Male[edit] In a male, it develops into a system of connected organs between the efferent ducts of the testis and the prostate, namely the epididymis, the vas deferens, and the seminal vesicle. The prostate forms from the urogenital sinus and the efferent ducts form from the mesonephric tubules. For this it is critical that the ducts are exposed to testosterone during embryogenesis. Testosterone binds to and activates androgen receptor, affecting intracellular signals and modifying the expression of numerous genes.[1] In the mature male, the function of this system is to store and mature sperm, and provide accessory semen fluid. Female[edit] In the female, with the absence of anti-Müllerian hormone secretion by the Sertoli cells and subsequent Müllerian apoptosis, the Wolffian duct regresses, and inclusions may persist. The epoophoron and Skene's glands may be present. Also, lateral to the wall of the vagina a Gartner's duct or cyst could develop as a remnant.


Function[edit] Sexual differentiation[edit] Main article: Sexual differentiation


History[edit] It is named after Caspar Friedrich Wolff who described the mesonephros and its ducts in his dissertation in 1759.[2]


Additional images[edit] Diagram of a transverse section, showing the mode of formation of the amnion in the chick. Reconstruction of a human embryo of 17 mm. Cloaca of human embryo from twenty-five to twenty-seven days old. Broad ligament of adult, showing epoophoron. Transverse section of human embryo eight and a half to nine weeks old. Tail end of human embryo twenty-five to twenty-nine days old. Tail end of human embryo thirty-two to thirty-three days old. Tail end of human embryo; from eight and a half to nine weeks old. Primitive kidney and bladder, from a reconstruction.


See also[edit] Fetal genital development List of homologues of the human reproductive system Masculinization Müllerian duct Sexual differentiation


References[edit] ^ Hannema SE, Print CG, Charnock-Jones DS, Coleman N, Hughes IA (2006). "Changes in gene expression during Wolffian duct development". Horm. Res. 65 (4): 200–9. doi:10.1159/000092408. PMID 16567946.  ^ synd/2845 at Who Named It?


External links[edit] MedicalMnemonics.com: 1266 How the Body Works / Sex Development / Sexual Differentiation / Duct Differentiation - The Hospital for Sick Children (GTA - Toronto, Ontario, Canada) v t e Sex determination and differentiation Overview Sexual differentiation humans Development of the reproductive system gonads Mesonephric duct Paramesonephric duct Genetic basis Sex-determination system XY X0 ZW Temperature-dependent Haplodiploidy Sex chromosome X chromosome Y chromosome Testis-determining factor See also Hermaphrodite Intersex Disorders of sex development v t e Development of the reproductive system Precursors Mesoderm intermediate lateral plate Endoderm Cloaca Urogenital sinus Ectoderm Cloacal membrane Internal Development of the gonads Gonadal ridge Pronephric duct Mesonephric duct Paramesonephric duct Vaginal plate Definitive urogenital sinus External Genital tubercle Labioscrotal swelling Primordial phallus Gubernaculum Peritoneum Vaginal process Canal of Nuck See also List of related male and female reproductive organs Prenatal development Embryogenesis v t e Development of the reproductive system Precursors Mesoderm intermediate lateral plate Endoderm Cloaca Urogenital sinus Ectoderm Cloacal membrane Internal Development of the gonads Gonadal ridge Pronephric duct Mesonephric duct Paramesonephric duct Vaginal plate Definitive urogenital sinus External Genital tubercle Labioscrotal swelling Primordial phallus Gubernaculum Peritoneum Vaginal process Canal of Nuck See also List of related male and female reproductive organs Prenatal development Embryogenesis Retrieved from "https://en.wikipedia.org/w/index.php?title=Mesonephric_duct&oldid=803564538" Categories: Embryology of urogenital systemHidden categories: Medicine infobox template using GraySubject or GrayPage


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Mesonephric_duct - Photos and All Basic Informations

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Urogenital SinusEmbryoCarnegie StagesEmbryologyIntermediate MesodermEmbryologyVas DeferensSeminal VesiclesEpididymisLatinTerminologia EmbryologicaAnatomical TerminologyOrgan (anatomy)HumanEmbryogenesisUrogenitalEpididymisVas DeferensSeminal VesicleMesonephrosCloacaAnlage (biology)Reproductive OrganMesonephrosCloacaAnlage (biology)Reproductive OrganEnlargeEnlargeCloacaMammalUrogenital SinusUrinary BladderUreterRectumTrigone Of Urinary BladderDevelopment Of The Urinary And Reproductive OrgansMaleEfferent DuctsTestisEpididymisVas DeferensSeminal VesicleProstateUrogenital SinusMesonephric TubulesTestosteroneEmbryogenesisTestosteroneAndrogen ReceptorSpermatozoonSemenFemaleAnti-Müllerian HormoneSertoli CellsEpoophoronSkene's GlandsGartner's DuctSexual DifferentiationCaspar Friedrich WolffMesonephrosDissertationEdit Section: See AlsoFetal Genital DevelopmentList Of Homologues Of The Human Reproductive SystemMasculinizationMüllerian DuctSexual DifferentiationDigital Object IdentifierPubMed IdentifierWho Named It?MnemonicThe Hospital For Sick ChildrenTemplate:Sex Determination And DifferentiationTemplate Talk:Sex Determination And DifferentiationSex-determination SystemSexual DifferentiationSexual DifferentiationSexual Differentiation In HumansDevelopment Of The Reproductive SystemDevelopment Of The GonadsParamesonephric DuctSex-determination SystemXY Sex-determination SystemX0 Sex-determination SystemZW Sex-determination SystemTemperature-dependent Sex DeterminationHaplodiploidyAllosomeX ChromosomeY ChromosomeTestis-determining FactorHermaphroditeIntersexDisorders Of Sex DevelopmentTemplate:Development Of The Reproductive SystemTemplate Talk:Development Of The Reproductive SystemDevelopment Of The Reproductive SystemMesodermIntermediate MesodermLateral Plate MesodermEndodermCloaca (embryology)Urogenital SinusEctodermCloacal MembraneDevelopment Of The GonadsGonadal RidgePronephric DuctParamesonephric DuctVaginal PlateUrogenital SinusGenital TubercleLabioscrotal SwellingPrimordial PhallusGubernaculumPeritoneumVaginal ProcessCanal Of NuckList Of Related Male And Female Reproductive OrgansPrenatal DevelopmentEmbryogenesisTemplate:Development Of The Reproductive SystemTemplate Talk:Development Of The Reproductive SystemDevelopment Of The Reproductive SystemMesodermIntermediate MesodermLateral Plate MesodermEndodermCloaca (embryology)Urogenital SinusEctodermCloacal MembraneDevelopment Of The GonadsGonadal RidgePronephric DuctParamesonephric DuctVaginal PlateUrogenital SinusGenital TubercleLabioscrotal SwellingPrimordial PhallusGubernaculumPeritoneumVaginal ProcessCanal Of NuckList Of Related Male And Female Reproductive OrgansPrenatal DevelopmentEmbryogenesisHelp:CategoryCategory:Embryology Of Urogenital SystemCategory:Medicine Infobox Template Using GraySubject Or GrayPageDiscussion About Edits From This IP Address [n]A List Of Edits Made From This IP Address [y]View The Content Page [c]Discussion About The Content Page [t]Edit This Page [e]Visit The Main Page [z]Guides To Browsing WikipediaFeatured Content – The Best Of WikipediaFind Background Information On Current EventsLoad A Random Article [x]Guidance On How To Use And Edit WikipediaFind Out About WikipediaAbout The Project, What You Can Do, Where To Find ThingsA List Of Recent Changes In The Wiki [r]List Of All English Wikipedia Pages Containing Links To This Page [j]Recent Changes In Pages Linked From This Page [k]Upload Files [u]A List Of All Special Pages [q]Wikipedia:AboutWikipedia:General Disclaimer



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