Contents 1 Public health and biosurveillance 2 Electronic records and medical practice management 3 Health system management 4 Prescriptions and medicines management 5 Disease management 6 Examination/diagnosis 7 Imaging/visualization 8 Medical information systems 9 Research 10 Mobile devices 11 Out-of-the-box distributions 12 Interoperability 13 Specifications 14 See also 15 References 16 Further reading


Public health and biosurveillance[edit] Epi Info is public domain statistical software for epidemiology developed by Centers for Disease Control and Prevention.[1] Spatiotemporal Epidemiological Modeler is a tool, originally developed at IBM Research, for modelings and visualizing the spread of infectious diseases. It is maintained by the Eclipse Foundation and available under terms of the Eclipse Public License.[2][3]


Electronic records and medical practice management[edit] Name Maintainer License Programming language/ Software stack Operating System Features Target setting EHR/EMR HIS? Practice management? Other Bahmni ThoughtWorks Technologies[4] GNU AGPL[4] OpenMRS; JavaScript[4] ? EMR Yes ? Low resource environments ClearHealth ClearHealth Inc.[5] GNU GPL[5] PHP, JavaScript[6] ? EMR ? Scheduling & billing HIPAA security CottageMed ? GNU GPL[7] FileMaker Cross-platform[7] EMR[7] ? ? Prescriptions[7] FreeMED FreeMED Software Foundation[8] GNU GPL[9] ? ? Yes ? Yes HIPAA compliant FreeMedForms EMR ? Debian-compatible[10] ? Cross-platform[10] EMR ? ? Medical software suite International ERPNext Frappe Technologies GNU GPL[11] Python; JavaScript ? EMR Yes Yes GaiaEHR ? GNU GPL[12] PHP & Ext JS ? EHR ? ? GNUmed GNUmed GNU GPL[13] Python (wxPython); PostgreSQL[13] Cross-platform[13] Yes[13] No ? GNU Health GNU Health (GNU Project) GNU GPL[14] Python (wxPython); PostgreSQL Cross-platform EMR[14] Yes[14] Yes[14] Hospital OS ? GNU GPL[15] Java[15] Linux & Windows[15] ? Yes ? Small Thai hospitals[15] HospitalRun ? GNU GPL[16] ? ? EMR ? ? Offline-first Hospitals in developing countries HOSxP ? Public domain[17] Delphi/Kylix[17] Windows[17] EHR Yes[17] Financial[17] Thai hospitals[17] MedinTux MedinTux team[18] CeCILL[18] C++[19] Cross-platform[20] ? ? Yes Modular design; web[21] & desktop interfaces French hospital emergency departments & smaller practices Odoo Medical LasLabs & Odoo Community Association[22] Affero GPL[22] Odoo[22] ? ? Yes ? Family medicine & primary healthcare OpenClinic ? GNU GPL[23] PHP, JavaScript[23] Cross-platform[23] EMR ? ? Private clinics[23] OpenEMR ? GNU GPL[24] PHP, JavaScript; MySQL[25] Cross-platform[24] EMR[24] ? Yes[24] Patient portal & prescriptions[24] open-eObs Neova Health[26] GNU AGPL[27] Odoo; Python, JavaScript[28] ? Observation & clinical assessment Ward-level ? Real-time view of all patients National Health Service Open Dental Open Dental Software[29] GNU GPL[29] ? ? Dental record No Yes Dentistry OpenEyes ? GNU GPL[30] ? ? EMR ? ? Ophthalmology OpenHospital Informatici Senza Frontiere[31] GNU GPL[31] Java[31] Cross-platform[31] EMR Yes Yes Small rural hospitals openMAXIMS ? GNU AGPL[32] ? ? Yes Patient administration system ? Scalable Used in the National Health Service and applicable to other health systems OpenMRS OpenMRS Inc.[33] MPL with Healthcare Disclaimer[33] Java ? EMR ? ? Extensible & scalable OSCAR McMaster ? GNU GPL[34] ? ? EMR[34] ? Billing Web interface; PHR[34] Canadian healthcare providers OSEHRA VistA OSEHRA[35] Apache[36] ? ? EHR[35] ? ? Non-governmental use PopHealth OSEHRA Apache[37] ? ? Reporting engine No No Clinical Quality Measure database; web interface Ripple Ripple Foundation[38] Apache[38] JavaScript (Node.js)[38] ? Yes ? ? Integrated digital care record platform National Health Service SMART Pediatric Growth Chart Boston Children's Hospital[39] Apache[39] JavaScript[40] ? Growth charts ? ? FHIR-based Pediatrics Spinnaker Dental IT Ltd[41] GNU GPL[41] ? ? Dental record ? Yes Open Dental fork[42] UK dental practices[42] THIRRA ? MPL[43] PHP5 (CodeIgniter), JavaScript (jQuery);[43] PostgreSQL ? EHR[43] ? ? Disease surveillance;[43] web interface Ambulatory care & public health[43] VistA US Department of Veterans Affairs Free[35] ? ? EHR ? ? Veterans Health Administration facilities WorldVistA WorldVistA[35] GNU GPL[44] ? ? EHR[35] ? ? Non-governmental use ZEPRS Zcore Research Triangle Institute[45] Apache[45] Java[45] ? Yes ? ? Web interface


Health system management[edit] iHRIS is an integrated Human Resource Information System developed by IntraHealth International under USAID-funded CapacityPlus project and deployed in more than 20 countries in the world.[46] iHRIS is distributed under the GNU GPL.[47] DHIS is a district health management information system and data warehouse. DHIS2 is released under the BSD license.[48] HRHIS is a human resource for health information system for management of human resources for health developed by University of Dar es Salaam college of information and communication technology, Department of Computer Science and Engineering, for Ministry of Health and Social Welfare (Tanzania) and funded by the Japan International Cooperation Agency (JICA).[citation needed]


Prescriptions and medicines management[edit] OpenEP is a suite of medicines management apps that improve the safety and efficiency of prescribing and medicines management. It is available under the GNU AGPL.[49]


Disease management[edit] Breathing Games is a series of research-backed, co-created games to prevent, diagnose and treat chronic respiratory diseases. They are released under the Peer Production licence.[50] Nightscout is a collection of software tools, including mobile clients, to enable DIY cloud-based continuous glucose monitoring “…for informational and educational purposes.”[51] Individual components are available under various open-source licenses, including the GNU GPL,[52] GNU AGPL,[53] MIT License,[54] and BSD licenses.[55]


Examination/diagnosis[edit] Specvis is a desktop application designed for fast and reliable perimetry-like visual field examination. It is written in Java to ensure considerable portability and is licensed under GNU GPLv3.[56]


Imaging/visualization[edit] CamBA is a collection of neuroimaging pipelines distributed under the GNU GPL.[57] dcm4che is a DICOM based collection of Java applications and utilities for the healthcare enterprise. It is licensed under the GNU LGPL, GNU GPL, and Mozilla Public License.[58] Drishti is a volumetric visualization package for viewing computer tomography data. Able to import DICOM image stacks. It is available under the MIT license.[59] Endrov Image and data viewer and editor. It is available under the BSD license.[60] GIMIAS is a workflow-oriented environment focused on biomedical image computing and simulation. It is available under a BSD-style license.[61] Ginkgo CADx Cross-platform open source DICOM viewer and dicomizer. It is available under the GNU LGPL.[62] Horos is a DICOM medical image viewer. It is available under the GNU LGPL.[63] ImageVis3D volume rendering software for interactive visualization. It is available under the MIT license.[64] Insight Segmentation and Registration Toolkit (ITK) v4.0+ is released under the Apache license.[65] InVesalius 3D medical imaging reconstruction software. It is available under the GNU GPL.[66] ITK-SNAP Interactive software for 3D image navigation, annotation, and automatic segmentation. It is available under the GNU GPL.[67] MITK Medical Imaging Interaction Toolkit for interactive medical image processing. It is available under a BSD-style license.[68] Orthanc – Lightweight, RESTful DICOM server for medical imaging. It is available under the GNU GPL with OpenSSL exception; plugins may be released under other licenses.[69] OsiriX 3D DICOM medical viewer for Mac OS X. Complete DICOM Viewer with DICOM network support.[citation needed] ParaView large-scale visualization tool. It is available under the BSD license.[70] 3DSlicer Platform for medical image visualization and algorithm development. DICOM support, segmentation and registration, Diffusion MRI processing, and image guided surgery support. It is available under a BSD-style license.[71] Voreen volume rendering engine—a library for visually exploring volume data sets. DICOM is supported and Voreen is used in medical visualization as well as for visualizing electron microscopy data. It is available under the GNU GPL.[72] VTK is a visualization toolkit available under the BSD license.[73] Xebra is a medical imaging thin client available under the GNU GPL.[74]


Medical information systems[edit] Bika is an ISO 17025 laboratory information management system (LIMS) that combines web content management and workflow processing. It is available under the GNU GPL.[75] Caisis is a web-based information system for the storage and analysis of cancer patient data intended to bridge the gap between clinic and research. It is available under the GNU GPL.[76] cTAKES ("clinical Text Analysis Knowledge Extraction Software") is a natural language processing system for extracting information from electronic medical record clinical free-text, an Apache top level project (TLP) since 2013, developed by the Mayo Clinic and others. It is available under the Apache license.[77] MEDIC Client Registry RI is the Mohawk College MARC-HI/MEDIC Client Registry EMPI Implementation. It is available under the Apache license.[78]


Research[edit] ADAM is a genomics analysis platform with a focus on scalability and interoperability. It is available under the Apache license.[79] Bcbio is community developed genomics system that handles the data processing component of sequencing analysis. It is available under the MIT license.[80] Galaxy is a web platform for data-intensive biology using geographically-distributed supercomputers.[81] i2b2 is a National Institutes of Health-funded informatics framework for clinical genomics researchers. It is available under the i2b2 Software License.[82] LabKey Server is an extensible platform for integrating, analyzing and sharing all types of biomedical research data. It provides secure, web-based access to research data and includes a customizable data processing pipeline. It is distributed under the Apache license.[83] Open cancer is a cancer data management aiming to provide open data models, clinical pathways, prognostic scoring, and auto-identification of trial patients.[citation needed] Wregex is an amino acid motif searching software for weighted regular expressions. It is available under the GNU GPL.[84]


Mobile devices[edit] Glucosio allows people with diabetes to track their glucose levels while supporting diabetes research via Android or iOS mobile apps. The apps are released under the GNU GPL.[85] Medic Mobile combines SMS messaging, data collection, and analytics for health workers and health systems in hard-to-reach areas with or without internet connectivity. The web app is available under the Apache License.[86] OpenAPS is a set of development tools and documentation to support a DIY implementation of an artificial pancreas for people with Type 1 Diabetes. Common setups include the interfacing of CGMs, Insulin Pumps, and Raspberry Pi devices. It is released under the MIT license, but compatible medical devices are proprietary.[87] Ushahidi allows people to submit crisis information through text messaging using a mobile phone, email or web form. Displays information in map view. It is released under the GNU Affero General Public License, but some libraries use different licenses.[88]


Out-of-the-box distributions[edit] BioLinux Debian-Med is a Debian Pure Blend for use in medical and biomedical settings.[89] Ubuntu-Med


Interoperability[edit] Cypress is maintained by MITRE Corporation with funding from the Centers for Medicare and Medicaid Services and the Office of the National Coordinator for Health Information Technology (ONC).[90] It is used to test EHR software for compliance with the Meaningful Use Stage 2 Clinical Quality Measures.[91] Cypress is distributed under the Apache license.[90] Laika was developed by the Certification Commission for Healthcare Information Technology (CCHIT) and MITRE to test EHR software for compliance with CCHIT interoperability data standards, including the HITSP C32 XML and HL7 v2 Lab messages. Laika is available under the Apache license.[92] Mirth is an open source cross-platform HL7 interface engine that enables bi-directional sending of HL7 messages between systems and applications over multiple transports. It is available under the Mozilla Public License.[93]


Specifications[edit] Continuity of Care Document Fast Healthcare Interoperability Resources (FHIR) is a Health Level 7 interoperability specification that defines JSON and XML data formats and a RESTful API.[94][95] It is available under the CC0 license.[96] openEHR is an open standard specification in health informatics that describes the management and storage, retrieval and exchange of health data in electronic health records (EHRs) following a two-level modeling paradigm. The OpenEHR base specification is available under the Creative Commons Attribution-ShareAlike 3.0 Unported license.[97]


See also[edit] Free software portal Electronic medical record eHealth Gello Expression Language Health informatics Hospital information systems List of freeware health software List of biomedical cybernetics software List of open-source bioinformatics software List of open-source health hardware mHealth


References[edit] ^ "Epi Info". CDC. 13 September 2016.  ^ "Download STEM". Eclipse. 22 June 2017.  ^ "Eclipse Foundation Software User Agreement". Eclipse. 9 April 2014.  ^ a b c "Frequently Asked Questions". Bahmni. Retrieved 29 June 2017.  ^ a b "clearhealth/LICENSE". GitHub. 30 January 2013.  ^ "clearhealth/clearhealth". GitHub. Retrieved 30 June 2017.  ^ a b c d "CottageMed™ EHR". SourceForge. 7 August 2015.  ^ "FreeMED Software Foundation". Retrieved 8 July 2017.  ^ "freemed/LICENSE". GitHub. 25 January 2012.  ^ a b "Download center of the FreeMedForms project". FreeMedForms. Retrieved 29 June 2017.  ^ "ERPNext Healthcare/LICENSE". GitHub. 29 January 2016.  ^ "gaiaehr/LICENSE". GitHub. 29 January 2016.  ^ a b c d "Gnumed FAQs". Gnumed. 10 October 2011.  ^ a b c d "GNU Health - Summary". Savannah. Retrieved 29 June 2017.  ^ a b c d "Hospital OS". SourceForge. 10 April 2013.  ^ "hospitalrun-frontend/LICENSE". GitHub. 28 March 2014.  ^ a b c d e f "HOSxP". SourceForge. 17 April 2013.  ^ a b "À propos" [About]. Medintux (in French). Retrieved 30 June 2017.  ^ "dev". Medintux (in French). 29 June 2012.  ^ "Installation". Medintux (in French). Retrieved 10 July 2017.  ^ "MedWebTux". Medintux (in French). 13 July 2013.  ^ a b c "Odoo Medical". Odoo. Retrieved 29 June 2017.  ^ a b c d Chavarría, Jose Antonio. "What is OpenClinic?". OpenClinic Project. Retrieved 30 June 2017.  ^ a b c d e "OpenEMR Features". OpenEMR. 6 May 2017.  ^ "Development Policies". OpenEMR Project Wiki. 17 April 2017.  ^ "open-eObs". Retrieved 30 June 2017.  ^ "openeobs/LICENSE". GitHub. 20 November 2015.  ^ "NeovaHealth/openeobs". GitHub. Retrieved 30 June 2017.  ^ a b "Open Source License". Open Dental. Retrieved 29 June 2017.  ^ "OpenEyes/README.md". GitHub. 12 October 2016.  ^ a b c d "Open Hospital". SourceForge. 4 June 2017.  ^ "openMAXIMS/LICENCE.TXT". GitHub. 13 June 2014.  ^ a b "OpenMRS License Information". OpenMRS. Retrieved 29 June 2017.  ^ a b c "Welcome". OSCAR User's Manual. Retrieved 29 June 2017.  ^ a b c d e "Distributions of VistA". OSEHRA. Retrieved 29 June 2017.  ^ "VistA/LICENSE". GitHub. 6 November 2012.  ^ "popHealth". OSEHRA. March 2017.  ^ a b c "Ripple-Qewd/README.md". GitHub. 14 June 2017.  ^ a b "growth-chart-app/LICENSE". GitHub. 23 June 2015.  ^ "smart-on-fhir/growth-chart-app". GitHub. Retrieved 30 June 2017.  ^ a b "Welcome to Spinnaker". Spinnaker. Dental IT Ltd. Retrieved 30 June 2017.  ^ a b "Spinnaker". Dental IT Ltd. Retrieved 30 June 2017.  ^ a b c d e "THIRRA Electronic Health Records Systems". SourceForge. 31 January 2017.  ^ "WorldVistA EHR GPL License". WorldVistA. Retrieved 30 June 2017.  ^ a b c "Licensing". ICTedge. Archived from the original on 10 September 2014.  ^ "About iHRIS". iHRIS. Retrieved 3 July 2017.  ^ "Frequently Asked Questions". iHRIS. Retrieved 30 June 2017.  ^ "DHIS 2 Overview". DHIS2. Retrieved 30 June 2017.  ^ "OPENeP". Medical Free/Libre Open Source Software. Retrieved 30 June 2017.  ^ "Get Involved". Breathing Games. 17 December 2016.  ^ "The Nightscout Project". Retrieved 3 July 2017.  ^ "android-uploader/LICENSE". GitHub. 27 September 2014.  "lasso/LICENSE". GitHub. 2 July 2015.  "chrome-uploader/LICENSE.md". GitHub. 24 November 2014.  "windows-phone-app/LICENSE". GitHub. 29 November 2014.  ^ "cgm-remote-monitor/LICENSE". GitHub. 25 September 2014.  "process-controls/LICENSE". GitHub. 11 January 2015.  ^ "nightscout-apple-watch/LICENSE". GitHub. 23 June 2015.  ^ "fda-presubmission/LICENSE". GitHub. 24 June 2014.  "cgm-pebble/LICENSE". GitHub. 22 February 2014.  ^ Dzwiniel, Piotr; Gola, Mateusz; Wójcik-Gryciuk, Anna; Waleszczyk, Wioletta J. (13 October 2017). "Specvis: Free and open-source software for visual field examination". PLOS ONE. 12 (10): e0186224. doi:10.1371/journal.pone.0186224. ISSN 1932-6203. PMID 29028825.  ^ "CamBA: Tool/Resource Info". NITRC. Neuroimaging Informatics Tools and Resources Clearinghouse. Retrieved 3 July 2017.  ^ "dcm4che, a DICOM Implementation in JAVA". SourceForge. June 2017.  ^ "drishti/license.md". GitHub. 1 February 2016.  ^ "Endrov". SourceForge. 3 January 2016.  ^ "License". GIMIAS. Retrieved 30 June 2017.  ^ "Ginkgo CADx". Retrieved 30 June 2017.  ^ "Horos". Horos Project. Retrieved 30 June 2017.  ^ "ImageVis3D". Scientific Computing and Imaging Institute. University of Utah. Retrieved 30 June 2017.  ^ "Copyright and License". ITK. Kitware.  ^ "invesalius3/LICENSE.txt". GitHub. 10 June 2009.  ^ "ITK-SNAP". NITRC. Neuroimaging Informatics Tools and Resources Clearinghouse. Retrieved 30 June 2017.  ^ "License". MITK. 1 December 2014.  ^ "Download". Orthanc. Retrieved 30 June 2017.  ^ "ParaView License". ParaView. Retrieved 30 June 2017.  ^ "License". SlicerWiki. 24 November 2016.  ^ "About Voreen". Voreen. Retrieved 30 June 2017.  ^ "License". VTK. Retrieved 30 June 2017.  ^ "Xebra". SourceForge. 17 April 2013.  ^ "bika.lims/LICENSE.txt". GitHub. 26 May 2017.  ^ "Frequently Asked Questions". Caisis. BioDigital. Retrieved 30 June 2017.  ^ "History". cTAKES. Apache Software Foundation. Retrieved 30 June 2017.  ^ "MEDIC Client Registry RI - License". CodePlex. 23 June 2015.  ^ "adam/LICENSE.txt". GitHub. 21 April 2013.  ^ "bcbio-nextgen/LICENSE.txt". GitHub. 18 July 2013.  ^ "Copyrights and Licenses". Galaxy Wiki. 14 May 2015.  ^ "i2b2 Software License". i2b2. Partners Healthcare. 15 January 2009.  ^ "FAQ - Frequently Asked Questions". LabKey Support. Retrieved 30 June 2017.  ^ "Home". Wregex. 12 May 2016.  ^ "glucosio-android/LICENSE". GitHub. 19 August 2015.  "glucosio-ios/LICENSE". GitHub. 19 August 2015.  ^ "medic-webapp/README.md". GitHub. 30 June 2017.  ^ "LICENSE.txt". GitHub. 26 August 2017.  ^ "platform/LICENSE.md". GitHub. 18 November 2014.  ^ "Debian Med". Debian. Software in the Public Interest, Inc. 5 July 2016.  ^ a b "FAQ". Cypress. 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Further reading[edit] "Medical Free/Libre and Open Source Software". IMIA Open Source Working Group. Retrieved 3 July 2017.  Millard, Peter S.; Bru, Juan; Berger, Christopher A. (4 July 2012). "Open-source point-of-care electronic medical records for use in resource-limited settings: systematic review and questionnaire surveys". BMJ Open. 2 (4): e000690. doi:10.1136/bmjopen-2011-000690. PMC 3391372 . PMID 22763661.  v t e Free healthcare software DICOM Client 3DSlicer Drishti GIMIAS Ginkgo CADx InVesalius ITK-SNAP OsiriX Voreen Xebra Server Orthanc Xebra Operating systems BioLinux Debian-Med Ubuntu-Med Practice management ClearHealth FreeMED GNU Health MedinTux Open Dental OpenEMR Records CottageMed FreeMED GNUmed GNU Health Hospital OS HOSxP Mirth OpenEMR OpenMRS OSCAR McMaster THIRRA (EHR) VistA ZEPRS v t e Health software Barcoding Bar Code Medication Administration Databases ACP Smart Medicine Epocrates Lexicomp Medscape Micromedex Diagnostics Bioimaging DICOM General 3DSlicer Drishti GIMIAS Ginkgo CADx InVesalius ITK-SNAP OsiriX VistA imaging Voreen Xebra Servers Orthanc Xebra Heuristics Bestbets CommonGround EuResist Odontologic Cybermed Florida Probe Electronic health records Platforms Apache cTAKES AHLTA athenaClinicals Centricity EMR Certify HealthLogix Cerner EHR CottageMed COSTAR Datix DocNetwork Dossia EMIAS EMIS Web EpicCare EMR FreeMED GaiaEHR GNUmed GPASS HOSxP INPS Vision Kareo EHR MedcomSoft Record MTBC WebEHR2.0 NextGen Healthcare NHS Care Records Service NHS Connecting for Health OpenEMR OpenMRS Practice Fusion SmartCare Summary Care Record TextID TPP SystmOne Vetter Software VistA VITAband World Medical Card ZEPRS Terminology Read code SNOMED CT LOINC UCUM RxNorm Laboratory management ELab LabKey Server STARLIMS webLIMS Patient portals athenaCommunicator Cerner Patient Portal MyChart Personal health records Dossia Microsoft HealthVault Google Health (discontinued) Practice management Billing Kareo Medical Billing Practice Fusion Billing Comprehensive ClearHealth Kareo Practice Management NueMD OpenHospital Specialty Dental Dentrix Open Dental SoftDent Scheduling EatherWay Kareo Zocdoc Vezeeta Patient engagement Kareo Vezeeta Research Behavioral PEBL Presentation PsychoPy Psychtoolbox for MATLAB PsyScope Cancer Caisis Folding@home Clinical trials Oracle Argus Surgical Assistive HipNav Transmission eMix Microsoft Amalga Mirth Connect Related 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