Contents 1 Structure 1.1 Male 1.2 Female 2 Development 3 Reproduction 3.1 Production of gametes 4 Disease 5 References

Structure[edit] Male[edit] Main article: Human male reproductive system The male reproductive system is a series of organs located outside of the body and around the pelvis region of a male that contribute towards the reproduction process. The primary direct function of the male reproductive system is to provide the male sperm for fertilization of the ovum. The major reproductive organs of the male can be grouped into three categories. The first category is sperm production and storage. Production takes place in the testes which are housed in the temperature regulating scrotum, immature sperm then travel to the epididymis for development and storage. The second category are the ejaculatory fluid producing glands which include the seminal vesicles, prostate, and the vas deferens. The final category are those used for copulation, and deposition of the spermatozoa (sperm) within the male, these include the penis, urethra, vas deferens, and Cowper's gland also called bulbo-urethral gland. Major secondary sexual characteristics includes: larger, more muscular stature, deepened voice, facial and body hair, broad shoulders, and development of an adam's apple. An important sexual hormone of males is androgen, and particularly testosterone. The testes release a hormone that controls the development of sperm. This hormone is also responsible for the development of physical characteristics in men such as facial hair and a deep voice. Female[edit] Main article: Human female reproductive system The human female reproductive system is a series of organs primarily located inside of the body and around the pelvic region of a female that contribute towards the reproductive process. The human female reproductive system contains three main parts: the vulva, which leads to the vagina, the vaginal opening, to the uterus; the uterus, which holds the developing fetus; and the ovaries, which produce the female's ova. The breasts are involved during the parenting stage of reproduction, but in most classifications they are not considered to be part of the female reproductive system. The vagina meets the outside at the vulva, which also includes the labia, clitoris and urethra; during intercourse this area is lubricated by mucus secreted by the Bartholin's glands. The vagina is attached to the uterus through the cervix, while the uterus is attached to the ovaries via the fallopian tubes. Each ovary contains hundreds of egg cells or ova (singular ovum). Approximately every 28 days, the pituitary gland releases a hormone that stimulates some of the ova to develop and grow. One ovum is released and it passes through the fallopian tube into the uterus. Hormones produced by the ovaries prepare the uterus to receive the ovum. The lining of the uterus, called the endometrium, and unfertilized ova are shed each cycle through the process of menstruation. If the ovum is fertilized by sperm, it attaches to the endometrium and the fetus develops.

Development[edit] Main article: Development of the reproductive system The development of the reproductive system and the development of the urinary system are closely tied in the development of the human fetus. Despite the differences between the adult female and male are derived from the intermediate mesoderm. The three main fetal precursors of the reproductive organs are the Wolffian duct, Müllerian ducts, and the gonad. Endocrine hormones are a well known and critical controlling factor in the normal differentiation of the reproductive system.[2] The Wolffian duct forms the epididymis, vas deferens, ductus deferens, ejaculatory duct, and seminal vesicle in the male reproductive system and essentially disappears in the female reproductive system. For the Müllerian Duct this process is reversed as it essentially disappears in the male reproductive system and forms the fallopian tubes, uterus, and vagina in the female system. In both sexes the gonad goes on to form the testes and ovaries, because they are derived from the same undeveloped structure they are considered homologous organs. There are a number of other homologous structures shared between male and female reproductive systems. However, despite the similarity in function of the female fallopian tubes and the male epididymis and vas deferens, they are not homologous but rather analogous structures as they arise from different fetal structures.

Reproduction[edit] Further information: Human reproduction Production of gametes[edit] Main articles: Spermatogenesis and Oogenesis The production of gametes takes place within the gonads through a process known as gametogenesis. Gametogenesis occurs when certain types of germ cells undergo meiosis to split the normal diploid number of chromosome(n=46) into haploids cells containing only 23 chromosomes.[3] In males, this process is known as spermatogenesis and takes place only after puberty in the seminiferous tubules of the testes. The immature spermatozoon or sperm are then sent to the epididymis where they gain a tail and motility. Each of the original diploid germs cells or primary spermatocytes forms four functional gametes which is each forever young. The production and survival of sperms require a temperature that is lower than the normal core body temperature. Since the scrotum, where the testes is present, is situated outside the body cavity, it provides a temperature about 3 °C below normal body temperature. In females, gametogenesis is known as oogenesis which occurs in the ovarian follicles of the ovaries. This process does not produce mature ovum until puberty. In contrast with males, each of the original diploid germ cells or primary oocytes will form only one mature ovum, and three polar bodies which are not capable of fertilization It has long been understood that in females, unlike males, all of the primary oocytes ever found in a female will be created prior to birth, and that the final stages of ova production will then not resume until puberty.[3] However, recent scientific data has challenged that hypothesis.[4] This new data indicates that in at least some species of mammal oocytes continue to be replenished in females well after birth.[5]

Disease[edit] Main article: Reproductive system disease Like all complex organ systems the human reproductive system is affected by many diseases. There are four main categories of reproductive diseases in humans. They are: 1) genetic or congenital abnormalities, 2) cancers, 3) infections which are often sexually transmitted diseases, and 4) functional problems cause by environmental factors, physical damage, psychological issues, autoimmune disorders, or other causes. The best known type of functional problems include sexual dysfunction and infertility which are both broad terms relating to many disorders with many causes. The human reproductive system usually involves internal fertilization by sexual intercourse. During this process, the male inserts his erect penis into the female's vagina and ejaculates semen, which contains sperm. The sperm then travels through the vagina and cervix into the uterus or fallopian tubes for fertilization of the ovum. Upon successful fertilization and implantation, gestation of the fetus then occurs within the female's uterus for approximately nine months, this process is known as pregnancy in humans. Gestation ends with birth, the process of birth is known as labor. Labor consists of the muscles of the uterus contracting, the cervix dilating, and the baby passing out the vagina (the female genital organ). Human's babies and children are nearly helpless and require high levels of parental care for many years. One important type of parental care is the use of the mammary glands in the female breasts to nurse the baby.[1] Specific reproductive diseases are often symptoms of other diseases and disorders, or have multiple, or unknown causes making them difficult to classify. Examples of unclassifiable disorders include Peyronie's disease in males and endometriosis in females. Many congenital conditions cause reproductive abnormalities but are better known for their other symptoms, these include: Turner syndrome, Klinefelter's syndrome, Cystic fibrosis, and Bloom syndrome.[6]

References[edit] ^ a b Sexual Reproduction in Humans. 2006. John W. Kimball. Kimball's Biology Pages, and online textbook. ^ EDRI Federal Project Inventory: Cellular and Molecular Mechanisms of Abnormal Reproductive Development US EPA. Dr. William R. Kelce. 2006. ^ a b Development of sex cells in Reproductive system, Body Guide. Adam. ^ Tilly JL, Niikura Y, Rueda BR (August 2008). "The Current Status of Evidence for and Against Postnatal Oogenesis in Mammals: A Case of Ovarian Optimism Versus Pessimism?". Biol. Reprod. 80 (1): 2–12. doi:10.1095/biolreprod.108.069088. PMC 2804806 . PMID 18753611.  ^ Johnson J, Canning J, Kaneko T, Pru JK, Tilly JL (March 2004). "Germline stem cells and follicular renewal in the postnatal mammalian ovary". Nature. 428 (6979): 145–50. doi:10.1038/nature02316. PMID 15014492.  ^ Genetic Conditions > Reproductive system. 2007. Genetics Home Reference. U.S. National Library of Medicine. v t e Human systems and organs Musculoskeletal Skeletal system Bone Carpus Collar bone (clavicle) Thigh bone (femur) Fibula Humerus Mandible Metacarpus Metatarsus Ossicles Patella Phalanges Radius Skull Tarsus Tibia Ulna Rib Vertebra Pelvis Sternum Cartilage Joints Fibrous joint Cartilaginous joint Synovial joint Muscular system Muscle Tendon Diaphragm Circulatory system Cardiovascular system peripheral Artery Vein Lymphatic vessel Heart Lymphatic system primary Bone marrow Thymus secondary Spleen Lymph node CNS equivalent Glymphatic system Nervous system Brain Spinal cord Nerve Sensory system Ear Eye Integumentary system Skin Subcutaneous tissue Breast Mammary gland Immune system Myeloid Myeloid immune system Lymphoid Lymphoid immune system Respiratory system Upper Nose Nasopharynx Larynx Lower Trachea Bronchus Lung Digestive system Mouth Salivary gland Tongue upper GI Oropharynx Laryngopharynx Esophagus Stomach lower GI Small intestine Appendix Colon Rectum Anus accessory Liver Biliary tract Pancreas Urinary system Genitourinary system Kidney Ureter Bladder Urethra Reproductive system Female Uterus Vagina Vulva Ovary Placenta Male Scrotum Penis Prostate Testicle Seminal vesicle Endocrine system Pituitary Pineal Thyroid Parathyroid Adrenal Islets of Langerhans v t e Human physiology of sexual reproduction Menstrual cycle Menarche Menstruation Follicular phase Ovulation Luteal phase Gametogenesis Spermatogenesis (spermatogonium spermatocyte spermatid sperm) Oogenesis (oogonium oocyte ootid ovum) Germ cell (gonocyte gamete) Human sexual behavior Sexual arousal Sexual intercourse Masturbation Erection Orgasm Ejaculation Insemination Fertilisation/Fertility Implantation Pregnancy Postpartum period Mechanics of sex Life span Prenatal development/Sexual dimorphism/Sexual differentiation (Feminization Virilization) Puberty (Gonadarche Pubarche Menarche Spermarche Adrenarche) Maternal age / Paternal age Climacteric (Menopause Late-onset hypogonadism) Tanner scale Egg Ovum Oviposition Oviparity Ovoviviparity Vivipary Reproductive endocrinology and infertility Hypothalamic–pituitary–gonadal axis Hypothalamic–pituitary–prolactin axis Andrology Hormone Breast Thelarche Breast development Lactation Breastfeeding Retrieved from "" Categories: Human anatomyReproductive systemSexual reproduction

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