References[edit] ^ a b c GRCh38: Ensembl release 89: ENSG00000129355 - Ensembl, May 2017 ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000096472 - Ensembl, May 2017 ^ "Human PubMed Reference:".  ^ "Mouse PubMed Reference:".  ^ Okuda T, Hirai H, Valentine VA, Shurtleff SA, Kidd VJ, Lahti JM, Sherr CJ, Downing JR (Mar 1996). "Molecular cloning, expression pattern, and chromosomal localization of human CDKN2D/INK4d, an inhibitor of cyclin D-dependent kinases". Genomics. 29 (3): 623–30. doi:10.1006/geno.1995.9957. PMID 8575754.  ^ a b "Entrez Gene: CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)". 


Further reading[edit] Hirai H, Roussel MF, Kato JY, et al. (1995). "Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6". Mol. Cell. Biol. 15 (5): 2672–81. PMC 230497 . PMID 7739547.  Chan FK, Zhang J, Cheng L, et al. (1995). "Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4". Mol. Cell. Biol. 15 (5): 2682–8. PMC 230498 . PMID 7739548.  Guan KL, Jenkins CW, Li Y, et al. (1996). "Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4". Mol. Biol. Cell. 7 (1): 57–70. doi:10.1091/mbc.7.1.57. PMC 278612 . PMID 8741839.  Schwaller J, Pabst T, Koeffler HP, et al. (1997). "Expression and regulation of G1 cell-cycle inhibitors (p16INK4A, p15INK4B, p18INK4C, p19INK4D) in human acute myeloid leukemia and normal myeloid cells". Leukemia. 11 (1): 54–63. doi:10.1038/sj.leu.2400522. PMID 9001419.  Russo AA, Tong L, Lee JO, et al. (1998). "Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a". Nature. 395 (6699): 237–43. doi:10.1038/26155. PMID 9751050.  Brotherton DH, Dhanaraj V, Wick S, et al. (1998). "Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d". Nature. 395 (6699): 244–50. doi:10.1038/26164. PMID 9751051.  Baumgartner R, Fernandez-Catalan C, Winoto A, et al. (1998). "Structure of human cyclin-dependent kinase inhibitor p19INK4d: comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16INK4a". Structure. 6 (10): 1279–90. doi:10.1016/S0969-2126(98)00128-2. PMID 9782052.  Schreiber M, Muller WJ, Singh G, Graham FL (1999). "Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity". Oncogene. 18 (9): 1663–76. doi:10.1038/sj.onc.1202466. PMID 10208428.  Newton Bishop JA, Harland M, Bennett DC, et al. (1999). "Mutation testing in melanoma families: INK4A, CDK4 and INK4D". Br. J. Cancer. 80 (1-2): 295–300. doi:10.1038/sj.bjc.6690354. PMC 2363010 . PMID 10390011.  Zindy F, Cunningham JJ, Sherr CJ, et al. (1999). "Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases". Proc. Natl. Acad. Sci. U.S.A. 96 (23): 13462–7. doi:10.1073/pnas.96.23.13462. PMC 23970 . PMID 10557343.  Thullberg M, Bartkova J, Khan S, et al. (2000). "Distinct versus redundant properties among members of the INK4 family of cyclin-dependent kinase inhibitors". FEBS Lett. 470 (2): 161–6. doi:10.1016/S0014-5793(00)01307-7. PMID 10734227.  Bartkova J, Thullberg M, Rajpert-De Meyts E, et al. (2000). "Lack of p19INK4d in human testicular germ-cell tumours contrasts with high expression during normal spermatogenesis". Oncogene. 19 (36): 4146–50. doi:10.1038/sj.onc.1203769. PMID 10962575.  Fink JR, LeBien TW (2001). "Novel expression of cyclin-dependent kinase inhibitors in human B-cell precursors". Exp. Hematol. 29 (4): 490–8. doi:10.1016/S0301-472X(01)00619-1. PMID 11301189.  Zeeb M, Rösner H, Zeslawski W, et al. (2002). "Protein folding and stability of human CDK inhibitor p19(INK4d)". J. Mol. Biol. 315 (3): 447–57. doi:10.1006/jmbi.2001.5242. PMID 11786024.  Matsuzaki Y, Miyazawa K, Yokota T, et al. (2002). "Molecular cloning and characterization of the human p19(INK4d) gene promoter". FEBS Lett. 517 (1-3): 272–6. doi:10.1016/S0014-5793(02)02647-9. PMID 12062451.  Arcellana-Panlilio MY, Egeler RM, Ujack E, et al. (2002). "Evidence of a role for the INK4 family of cyclin-dependent kinase inhibitors in ovarian granulosa cell tumors". Genes Chromosomes Cancer. 35 (2): 176–81. doi:10.1002/gcc.10108. PMID 12203782.  Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 . PMID 12477932.  Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.  Komata T, Kanzawa T, Takeuchi H, et al. (2004). "Antitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cells". Br. J. Cancer. 88 (8): 1277–80. doi:10.1038/sj.bjc.6600862. PMC 2747579 . PMID 12698196. 


External links[edit] CDKN2D human gene location in the UCSC Genome Browser. CDKN2D human gene details in the UCSC Genome Browser. v t e PDB gallery 1bd8: STRUCTURE OF CDK INHIBITOR P19INK4D  1bi8: MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX  v t e Cell cycle proteins Cyclin A (A1, A2) B (B1, B2, B3) D (D1, D2, D3) E (E1, E2) CDK 1 2 3 4 5 6 7 8 9 10 CDK-activating kinase CDK inhibitor INK4a/ARF (p14arf/p16, p15, p18, p19) cip/kip (p21, p27, p57) P53 p63 p73 family p53 p63 p73 Other Cdc2 Cdc25 Cdc42 Cellular apoptosis susceptibility protein E2F Maturation promoting factor Wee Cullin (CUL7) Phases and checkpoints Interphase G1 phase S phase G2 phase M phase Mitosis (Preprophase Prophase Prometaphase Metaphase Anaphase Telophase) Cytokinesis Cell cycle checkpoints Restriction point Spindle checkpoint Postreplication checkpoint Other cellular phases Apoptosis G0 phase Meiosis This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it. v t e Retrieved from "https://en.wikipedia.org/w/index.php?title=CDKN2D&oldid=797989703" Categories: Genes on human chromosome 19Human chromosome 19 gene stubsHidden categories: Articles with too few wikilinks from March 2014All articles with too few wikilinksArticles covered by WikiProject Wikify from March 2014All articles covered by WikiProject WikifyAll stub articles


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Wikipedia:Manual Of Style/LinkingWikipedia:BUILDWikipedia:Only Make Links That Are Relevant To The ContextHelp:Maintenance Template RemovalProtein Data BankGene NomenclatureMouse Genome InformaticsHomoloGeneGeneCardsChromosome 19 (human)ChromosomeChromosome 19 (human)Chromosome 19 (human)Genomic Location For CDKN2DGenomic Location For CDKN2DLocus (genetics)Base PairBase PairChromosome 9 (mouse)ChromosomeChromosome 9 (mouse)Genomic Location For CDKN2DGenomic Location For CDKN2DLocus (genetics)Base PairBase PairGene ExpressionGene OntologyEntrezEnsemblUniProtPubMedWikidataEnzymeGeneProteinGeneINK4Enzyme InhibitorKinasesSpermatogenesisEnsembl Genome Database ProjectEnsembl Genome Database ProjectDigital Object IdentifierPubMed IdentifierPubMed CentralPubMed IdentifierPubMed CentralPubMed IdentifierDigital Object IdentifierPubMed CentralPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed CentralPubMed IdentifierDigital Object IdentifierPubMed CentralPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed CentralPubMed IdentifierDigital Object IdentifierPubMed IdentifierDigital Object IdentifierPubMed CentralPubMed IdentifierUCSC Genome BrowserUCSC Genome BrowserTemplate:PDB GalleryTemplate Talk:PDB Gallery1bd8: STRUCTURE OF CDK INHIBITOR P19INK4D1bi8: MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEXTemplate:Cell Cycle ProteinsTemplate Talk:Cell Cycle ProteinsCell CycleProteinCyclinCyclin ACyclin A1Cyclin A2Cyclin BCyclin B1Cyclin B2Cyclin DCyclin D1Cyclin D2Cyclin D3Cyclin ECyclin E1Cyclin E2Cyclin-dependent KinaseCyclin-dependent Kinase 1Cyclin-dependent Kinase 2Cyclin-dependent Kinase 3Cyclin-dependent Kinase 4Cyclin-dependent Kinase 5Cyclin-dependent Kinase 6Cyclin-dependent Kinase 7Cyclin-dependent Kinase 8Cyclin-dependent Kinase 9Cyclin-dependent Kinase 10CDK-activating KinaseCyclin-dependent Kinase Inhibitor ProteinCell CycleP14arfP16CDKN2BCDKN2CCell CycleP21CDKN1BCyclin-dependent Kinase Inhibitor 1CP53 P63 P73 FamilyP53TP63P73Cdk1Cdc25CDC42Cellular Apoptosis Susceptibility ProteinE2FMaturation Promoting FactorWee1CullinCUL7InterphaseG1 PhaseS PhaseG2 PhaseCell DivisionMitosisPreprophaseProphasePrometaphaseMetaphaseAnaphaseTelophaseCytokinesisCell Cycle CheckpointRestriction PointSpindle CheckpointPostreplication CheckpointApoptosisG0 PhaseMeiosisGeneHuman Chromosome 19Wikipedia:StubTemplate:Gene-19-stubTemplate Talk:Gene-19-stubHelp:CategoryCategory:Genes On Human Chromosome 19Category:Human Chromosome 19 Gene StubsCategory:Articles With Too Few Wikilinks From March 2014Category:All Articles With Too Few WikilinksCategory:Articles Covered By WikiProject Wikify From March 2014Category:All Articles Covered By WikiProject WikifyCategory:All Stub ArticlesDiscussion About Edits From This IP Address [n]A List Of Edits Made From This IP Address [y]View The Content Page [c]Discussion About The Content Page [t]Edit This Page [e]Visit The Main Page [z]Guides To Browsing WikipediaFeatured Content – The Best Of WikipediaFind Background Information On Current EventsLoad A Random Article [x]Guidance On How To Use And Edit WikipediaFind Out About WikipediaAbout The Project, What You Can Do, Where To Find ThingsA List Of Recent Changes In The Wiki [r]List Of All English Wikipedia Pages Containing Links To This Page [j]Recent Changes In Pages Linked From This Page [k]Upload Files [u]A List Of All Special Pages [q]Wikipedia:AboutWikipedia:General Disclaimer



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